Shanghai Yung Zip Pharmaceutical Trading Co., Ltd.
We are especially known for our importing and exporting of Active Pharmaceutical Ingredients (API), pharmaceutical intermediates and pharmaceutical packaging.
Business Type:Trader
Country/Region:China
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| Product name: | Lovastatin |
| CAS: | 75330-75-5 |
| Chemical Properties: | White Solid |
| Molecular Formula: | C24H36O5 |
| Molecular Weight: | 404.54 |
| Uses: | An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase antiarrhythmic Lovastatin (mevinolin) is a metabolite first isolated from Monascus ruber and later found in several other fungal species. Lovastatin is a potent inhibitor of HMG-CoA. HMG-CoA reductase is the rate-controlling enzyme of the mevalonate pathway, responsible for the biosynthesis of cholesterol. Lovastatin was developed as a drug as a hypolipemic agent. anti-hyperlipoproteinemic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor |
| Biological Activity | Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro . |
Packaging Details:Delivery Detail:
| Customize |
| within 2 weeks after receiving payments |
